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. 2023 Apr 20;24(8):7554. doi: 10.3390/ijms24087554

Figure 4.

Figure 4

Data on the pumping of the ABCA3 variants: (A) volume of ABCA3+ vesicles; (B) PC from recycling into ABCA3+ vesicles; (C) PC from de novo synthesis into ABCA3+ vesicles; (D) ATPase activity of ABCA3. The green, dotted lines stand for ±1 nSD (fraction of WT nt). The purple, dotted lines stand for ±3 nSD (fraction of WT nt). The red, hollow circles represent data from this study. The red, solid circles represent data from our previous experiments. The red, semi-hollow triangles represent data from this study and the literature. The blue, semi-hollow triangles represent data from our previous experiments and the literature. The blue, solid triangles represent data from the literature. The black crosses represent that assays were not performed. The dark-grey shadow represents defective trafficking. The light-grey shadow represents impaired trafficking. No shadow: normal trafficking. The assay code refers to Figure 1.