Table 9.
Entry | X | R1 | R2 | Reaction Time | Yield (%) 2 |
---|---|---|---|---|---|
1 | I | H | H | 5 min | 94 |
2 | I | H | Me | 30 min | 91 |
3 | I | Me | H | 15 min | 92 |
4 | I | OMe | H | 20 min | 90 |
5 | I | NO2 | Me | 25 min | 91 |
6 | Br | NO2 | H | 1.2 h | 90 |
7 | Br | OMe | H | 18 h | 56 |
8 | Br | H | H | 17 h | 75 |
9 | - | H | 30 min | 90 | |
10 | Br | Me | H | 17 h | 55 |
11 | Cl | H | H | 18 h | 70 |
12 | H | H | 6 h | 60 |
1 Reaction conditions: aryl halide (1 mmol), n-butyl acrylate (1.5 mmol), n-Pr3N (1.5 mmol), LSA-PdNPs (0.05 g; 0.0028 mmol of Pd). 2 Isolated yields.