TABLE 6.
Predictors of Not Being Comprehensively Assessed Among Adultsa With TB (Without Known Drug-Resistant Disease at Diagnosis) with High Risk Of Severe Illnessb at Diagnosis That Were Notified by Public Facilities in Tamil Nadu, India, April–June 2022
| Baseline Characteristics c | Total, No. (%) d |
Not Comprehensively Assessed, No. (%)e |
RR | 95% CI | aRR f | 95% CI |
|---|---|---|---|---|---|---|
| Total | 1,509 (100) | 381 (25.3) | ||||
| Age, years | ||||||
| 15–24 | 144 (9.5) | 37 (25.7) | 1.02 | (0.72, 1.44) | 1.07 | (0.76, 1.50) |
| 25–34 | 168 (11.1) | 60 (35.7) | 1.41 | (1.05, 1.89) | 1.47 | (1.10, 1.95)g |
| 35–44 | 253 (16.8) | 64 (25.3) | Ref | Ref | ||
| 45–54 | 359 (23.8) | 97 (27.0) | 1.07 | (0.71, 1.40) | 1.07 | (0.82, 1.40) |
| 55–64 | 346 (22.9) | 74 (21.4) | 0.85 | (0.63, 1.13) | 0.87 | (0.65, 1.15) |
| ≥65 | 239 (15.8) | 49 (20.5) | 0.81 | (0.58, 1.12) | 0.88 | (0.63, 1.22) |
| Gender | ||||||
| Men | 1,062 (70.4) | 263 (24.8) | Ref | N/Ah | ||
| Women | 446 (29.6) | 117 (26.2) | 1.06 | (0.88, 1.28) | ||
| Transgender | 1 (0.07) | 1 (100.0) | -- | |||
| Test used for diagnosis | ||||||
| Rapid molecular tests | 213 (14.1) | 53 (24.9) | 0.99 | (0.77, 1.29) | ||
| Microscopy/culture | 927 (61.4) | 232 (25.0) | Ref | N/Ah | ||
| Chest radiograph | 153 (10.1) | 47 (30.7) | 1.23 | (0.94, 1.60) | ||
| Others | 216 (14.3) | 49 (22.7) | 0.91 | (0.69, 1.19) | ||
| Microbiological confirmation | ||||||
| Yes | 1,206 (79.9) | 298 (24.7) | Ref | N/Ah | ||
| No | 303 (20.1) | 83 (27.4) | 1.10 | (0.90, 1.37) | ||
| Site of TB | ||||||
| Pulmonary | 1,312 (86.9) | 334 (25.5) | Ref | N/Ah | ||
| Extrapulmonary | 175 (11.6) | 43 (24.6) | 0.97 | (0.73, 1.27) | ||
| Missing | 22 (1.5) | 4 (18.2) | 0.71 | (0.29, 1.74) | ||
| Previous treatment | ||||||
| Yes | 212 (14.1) | 47 (22.2) | 0.86 | (0.66, 1.13) | ||
| No | 1,297 (86.0) | 334 (25.8) | Ref | N/Ah | ||
| HIV | ||||||
| Positive | 65 (4.3) | 13 (20.0) | 0.78 | (0.48, 1.29) | ||
| Negative | 1,440 (95.4) | 367 (25.5) | Ref | N/Ah | ||
| Unknown | 4 (0.3) | 1 (25.0) | 0.98 | (0.18, 5.37) | ||
| DM | ||||||
| Positive | 325 (21.5) | 78 (24.0) | 0.93 | (0.75, 1.15) | ||
| Negative | 1,158 (76.7) | 300 (25.9) | Ref | N/Ah | ||
| Unknown | 5 (0.3) | 0 (0.0) | – | |||
| Missing | 21 (1.4) | 3 (14.3) | 0.55 | (0.19, 1.58) | ||
| Peripheral health institute—notification facility | ||||||
| Primary | 283 (18.8) | 111 (39.2) | 2.11 | (1.68, 2.65) | 1.90 | (1.52, 2.40)g |
| Secondary | 665 (44.1) | 166 (25.0) | 1.34 | (1.08, 1.67) | 1.26 | (1.01, 1.57)g |
| Tertiary | 555 (36.8) | 103 (18.6) | Ref | Ref | ||
| Missing | 6 (0.4) | 1 (16.7) | 0.90 | (0.15, 5.42) | 0.82 | (0.11, 5.88) |
| Very severe undernutritioni | ||||||
| Yes | 718 (47.6) | 190 (26.5) | 1.10 | (0.92, 1.30) | N/Ah | |
| No | 791 (52.4) | 191 (24.2) | Ref | |||
| Respiratory insufficiencyj | ||||||
| Yes | 747 (49.5) | 215 (28.8) | 1.32 | (1.11, 1.57) | 1.21 | (1.01, 1.45)g |
| No | 762 (50.5) | 166 (21.8) | Ref | Ref | ||
| Poor performance status (not able to stand without support) | ||||||
| Yes | 436 (28.9) | 64 (14.7) | 0.50 | (0.39, 0.63) | 0.60 | (0.46, 0.78)g |
| No | 1,072 (71.0) | 317 (29.6) | Ref | Ref | ||
| Missing | 1 (0.1) | 0 (0.0) | -- | – |
Abbreviations: aRR, adjusted relative risk; CI, confidence interval; DM, diabetes mellitus; N/A, not available; RR, crude relative risk; SeWA, Severe TB Web Application.
Aged 15 years and older.
Defined as the presence of any 1 indicator during triaging: body mass index ≤14 kg/m2/14.1–16.0 with bilateral pedal edema, respiratory rate >24 breaths/minute, oxygen saturation <94%, not able to stand without support.
Source is the routinely collected baseline data in NIKSHAY and data updated in TB SeWA as of July 29, 2022.
Column percentage.
Row percentage.
Modified Poisson regression with robust variance estimation; results have been adjusted for district.
P<0.05.
Variables with crude p value ≥ 0.05 (Chi square test) were not included in the adjusted analysis.
Body mass index ≤14 kg/m2/14.1–16.0 with bilateral pedal edema.
Respiratory rate >24 breaths/minute or oxygen saturation <94%.