Fig. 8.

Histological analysis of the regenerated tissue. The area of the new bone including CO₃Ap in the defect site (a), the height of the bone on the mesial side of the defect (b), and the length of the new PDL (c) and cementum (d) were measured. All results are expressed as mean +SD. Control, n = 4; CO₃Ap, n = 8; FGF-2+CO₃Ap, n = 8 at each time (white column: 6 weeks, black column: 24 weeks). ∗: P < 0.05, NS: not significant (CO₃Ap vs. FGF-2+CO₃Ap, a, and b, paired t-test at each time; c, and d; Wilcoxon's rank sum test at each time).