Table 2.
Characteristics of the patients affected by acquired or idiopathic histamine-mediated AEwW in pediatric age [9,38].
| Demographic, Personal History and Clinical Data | |
|---|---|
| Gender | Male |
| Average age at first-episode onset | 7–7.8 yrs |
| Average age at diagnosis | 8–9 yrs |
| Average length of relapse episode | 24 h |
| Number of exacerbation episodes in the last year | 2–5 |
| Most involved body areas | Eyelids, lips |
| Number of body areas involved during exacerbation episodes | Several |
| Personal history | Atopy |
| Familial history | Absence of family history related to recurrent AE episodes |
| Trigger factors | Infections, respiratory or food allergens, thyroid diseases, drugs (medical history of trauma is not frequent) |
| Response to antihistamine treatment | Symptoms improvement |
| Need for adrenaline or intubation | No |
| Prognosis | Good |