Table 3.
Overall frailty score and other factors independently associated with single and recurrent falls occurring approximately 10 years latera
| Single (versus 0) falls |
Recurrent (versus 0) falls |
|||||
|---|---|---|---|---|---|---|
| Adjusted odds ratio | 95% CI | P-value | Adjusted odds ratio | 95% CI | P-value | |
| HIV-positive | 0.85 | 0.58, 1.27 | 0.43 | 0.94 | 0.64, 1.38 | 0.75 |
| Frailty | 0.93 | 0.50, 1.75 | 0.83 | 1.84 | 1.13, 2.97 | 0.01 |
| Age (per 10 years) | – | – | – | 1.49 | 1.23, 1.82 | <0.0001 |
| Race (ref = White) | ||||||
| Black | 0.52 | 0.32, 0.86 | 0.01 | – | – | – |
| Hispanic/other | 1.45 | 0.81, 2.62 | 0.21 | – | – | – |
| Income ≥$12,000/year | – | – | – | 0.70 | 0.50, 0.99 | 0.04 |
| Marijuana use (ref = never) | ||||||
| Former | 1.71 | 1.06, 2.74 | 0.03 | 1.61 | 1.05, 2.47 | 0.03 |
| Current | 2.43 | 1.38, 4.25 | 0.002 | 2.09 | 1.23, 3.53 | 0.006 |
| Hypertension | 1.72 | 1.15, 2.57 | 0.009 | – | – | – |
| Neuropathy | 2.02 | 1.17, 3.49 | 0.01 | 2.30 | 1.45, 3.66 | 0.0004 |
| Obesity | – | – | – | 1.55 | 1.10, 2.18 | 0.01 |
| Number of CNS active medication classes | – | – | – | 1.44 | 1.17, 1.77 | 0.0006 |
Falls are reported over a 2-year period, approximately 10 years after measurement of frailty and other characteristics. Models also include study site. CNS, central nervous system.