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Trigger-dependent cellular cytotoxicity. (a, b) Potency in A549/HeLa cells. Note, e.g., consistent 13- to 30-fold greater toxicities in HeLa than in A549 cells for SS66C triggers (AZI or TMI cargos, P- or Me- substituents) (see also Table S1 and Figures S8 and S9).
