Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Histopathologic findings in a mouse model of immune complex (IC)-induced subcutaneous inflammation.
| Groups | PBS | TNFα | Ozoralizumab-TNFα IC1 | Ozoralizumab-TNFα IC2 | Adalimumab-TNFα ICs | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Number of animals | 3 | 3 | 3 | 3 | 3 | ||||||||||
| Grade | – | ± | + | – | ± | + | – | ± | + | – | ± | + | – | ± | + |
| Skin (injection site) | |||||||||||||||
| Subcutaneous neutrophil infiltration | 3 | 0 | 0 | 2 | 1 | 0 | 3 | 0 | 0 | 3 | 0 | 0 | 0 | 1 | 2 |
-, None/Negligible, ±, Minimal/Very slight, +, Mild/Slight.
ICs, immune complexes; PBS, phosphate-buffered saline; TNF, tumor necrosis factor.
