Figure 2.

Restricted Cubic Spline analyses for testing non-linearity associations. (A) GNRI; (B) PNI; (C) CONUT. The RCS analyses were adjusted for age (continuous), sex (female or male), tumor progression before RN (with or without); lower cranial nerves injury (with or without), bilateral necrosis (with or without), necrosis involving ≥ 2 brain regions (with or without), and history of stroke (with or without). The solid lines represent the hazard ratios, and the gray zones represent the 95% confidence interval. Abbreviations: RN, Radiation-induced brain necrosis; GNRI, Geriatric Nutritional Risk Index; PNI, Prognostic Nutritional Index; CONUT, Controlling Nutritional Status.