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. 2023 Apr 28;13:6950. doi: 10.1038/s41598-023-32180-9

Table 4.

Ergometry results of generalized linear mixed model (GLM model) analysis of 40 subjects without mask (NM) and with three different mask types (SM, CM, FFP2).

Pre (light work) E1 (moderate work) E2 (heavy work) E3 (very heavy work) Post (light work)
NM SM CM FFP2 NM SM CM FFP2 NM SM CM FFP2 NM SM CM FFP2 NM SM CM FFP2
G.M Δ
p value
G.M Δ
p value
G.M Δ
p value
G.M Δ
p value
G.M Δ
p value
Subjects’ perceived physical exertion

 BORG

(0–10)

0.81 − 0.05 − 0.04 − 0.18 0.96

0.05

0.651

0.22

0.306

0.33

0.022

2.14

0.33

0.384

0.23

0.522

0.89

0.008

3.68

0.59

0.360

0.54

0.419

1.21

0.016

0.88

0.11

0.498

0.14

0.475

0.22

0.064

Pulmonary parameters

 Ttot

(s)

2.90 0.31 0.31 0.6 2.45

0.14

0.239

0.20

0.577

0.20

0.007

2.28

0.03

0.012

0.05

0.022

0.04

 < 0.001

1.99

0.03

0.018

0.06

0.040

0.04

 < 0.001

2.44

0.15

0.250

0.13

0.176

0.07

 < 0.001

 RR

(min1)

19.48 − 1.75 − 1.51 − 3.06 23.69

− 1.20

0.257

− 1.62

0.791

− 1.89

0.018

25.69

− 0.18

0.010

− 0.30

0.040

− 0.5

 < 0.001

29.72

− 0.46

0.023

− 0.74

0.107

− 0.74

 < 0.001

23.69

− 1.64

0.543

− 1.01

0.312

− 0.67

 < 0.001

Metabolic parameters
 pH 7.42 0.00 − 0.01 − 0.01 7.41

− 0.01

0.109

− 0.02

0.096

− 0.02

0.158

7.40

− 0.02

0.060

− 0.02

0.030

− 0.02

0.163

7.39

− 0.03

0.001

− 0.03

0.001

− 0.04

 < 0.001

7.40

− 0.02

0.063

− 0.03

0.010

− 0.03

0.056

 pCO2 (mmHg) 36.01 0.31 − 0.22 0.50 36.69

1.60

0.079

1.31

0.033

2.09

0.033

36.36

1.93

0.023

2.17

0.001

2.92

0.001

34.58

3.04

 < 0.001

2.71

 < 0.001

4.71

 < 0.001

33.28

1.05

0.230

0.97

0.062

2.00

0.017

 pO2 (mmHg) 87.86 1.81 1.33 − 0.41 91.53

− 1.40

0.141

− 0.64

0.365

− 2.90

0.259

91.77

− 1.86

0.081

− 2.36

0.079

− 3.62

0.130

90.27

− 3.45

0.008

− 2.70

0.041

− 5.66

0.007

95.00

0.17

0.438

0.69

0.744

0.20

0.774

 Lactate (mmol/L) 1.36 0.00 − 0.08 − 0.03 1.69

− 0.07

0.621

− 0.05

0.715

− 0.09

0.672

2.51

− 0.03

0.864

0.01

0.435

− 0.10

0.798

4.50

− 0.13

0.688

− 0.06

0.561

− 0.07

0.971

3.61

0.00

0.980

0.09

0.294

0.02

0.767

 sO2

(%)

97.17 0.12 0.17 − 0.17 97.27

− 0.11

0.365

− 0.02

0.468

− 0.32

0.572

96.87

− 0.39

0.049

− 0.31

0.061

− 0.60

0.098

96.72

− 0.78

0.001

− 0.70

0.001

− 1.34

 < 0.001

97.17

0.13

0.980

0.04

0.594

− 0.16

0.956

 pH 7.42 0.00 − 0.01 − 0.01 7.41

− 0.01

0.109

− 0.02

0.096

− 0.02

0.158

7.40

− 0.02

0.060

− 0.02

0.030

− 0.02

0.163

7.39

− 0.03

0.001

− 0.03

0.001

− 0.04

 < 0.001

7.40

− 0.02

0.063

− 0.03

0.010

− 0.03

0.056

 pCO2 (mmHg) 36.01 0.31 − 0.22 0.50 36.69

1.60

0.079

1.31

0.033

2.09

0.033

36.36

1.93

0.023

2.17

0.001

2.92

0.001

34.58

3.04

 < 0.001

2.71

 < 0.001

4.71

 < 0.001

33.28

1.05

0.230

0.97

0.062

2.00

0.017

 pO2 (mmHg) 87.86 1.81 1.33 − 0.41 91.53

− 1.40

0.141

− 0.64

0.365

− 2.90

0.259

91.77

− 1.86

0.081

− 2.36

0.079

− 3.62

0.130

90.27

− 3.45

0.008

− 2.70

0.041

− 5.66

0.007

95.00

0.17

0.438

0.69

0.744

0.20

0.774

Hemodynamic parameters

 HR

(min− 1)

82.64 0.69 − 0.24 2.56 101.92

1.02

0.942

0.98

0.576

2.65

0.827

121.37

1.14

0.963

− 0.10

0.927

2.23

0.573

140.46

1.48

0.942

− 0.90

0.899

1.56

0.498

101.28

2.26

0.548

0.28

0.806

3.81

0.778

 SBP

(mmHg)

109.31 1.97 − 0.41 0.70 117.55

4.08

0.589

3.51

0.270

2.37

0.652

138.95

2.67

0.969

2.27

0.485

4.04

0.434

155.93

4.80

0.668

4.01

0.315

6.32

0.253

138.34

0.92

0.744

− 1.76

0.792

4.30

0.477

 DBP

(mmHg)

76.53 0.95 − 0.10 1.05 72.60

2.57

0.501

0.20

0.903

− 2.46

0.153

75.08

1.26

0.899

− 0.77

0.782

1.56

0.837

75.51

2.23

0.624

1.34

0.579

1.74

0.791

73.43

− 0.07

0.676

− 1.06

0.675

1.14

0.956

Capnometric parameters

 pCO2in

(mmHg)

1.63 0.75 0.86 0.99 1.83

0.57

0.680

0.57

0.947

1.06

0.021

1.89

0.60

0.643

0.65

0.793

1.46

 < 0.001

1.84

0.70

0.281

0.68

0.774

1.92

 < 0.001

1.83

0.52

0.243

0.66

0.500

1.33

0.061

 pCO2ex

(mmHg)

26.76 2.14 1.78 2.99 30.00

2.70

0.669

2.28

0.685

3.25

0.901

30.12

2.81

0.586

2.67

0.352

3.31

0.942

28.24

3.81

0.029

3.52

0.019

4.98

0.013

26.58

2.23

0.879

1.85

0.893

2.59

0.597

Mask microclimate
 Tmask (°C) 28.93 2.54 3.30 4.57 28.81

3.52

0.049

3.63

0.499

5.12

0.284

28.22

3.35

0.079

3.68

0.359

5.26

0.131

27.98

3.25

0.111

3.69

0.328

5.36

0.076

27.88

3.72

0.014

4.13

0.071

5.86

0.008

 RH (%) 43.56 23.74 31.38 29.28 42.81

29.95

0.101

36.60

0.195

33.24

0.297

41.70

31.12

0.043

39.58

0.040

35.23

0.105

45.39

29.28

0.289

36.55

0.415

34.08

0.437

48.95

28.42

0.690

35.30

0.992

33.41

0.913

BORG Borg scale, CM Community mask, DBP Diastolic blood pressure, Δ Difference to NM, FFP2 Filtering face piece class 2, G.M. Geometric mean, HR Heart rate, NM No mask, pCO2 Partial pressure of carbon dioxide, pO2 Partial pressure of oxygen, pCO2ex Expiratory carbon dioxide pressure, pCO2in Inspiratory carbon dioxide pressure, pH Potential of hydrogen in blood, RH Relative humidity, RR Respiratory rate, SBP Systolic blood pressure, sO2 Haemoglobin oxygen saturation, SM Surgical mask, Tin Inspiratory time, Tex Expiratory time, Tmask Temperature behind the mask, Ttot Inspiratory and expiratory time.

Masks were worn as in everyday life. The situation without mask in each specific load level (pre, E1, E2, E3, post) was always used as reference. For NM geometric mean (G.M.), for the three mask types (SM, CM, FFP2) differences to NM (Δ) and p values are shown.

Significant values are in bold.