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Goodness-of-fit plots for the final population pharmacokinetic model. A Polymyxin B concentration versus population predicted concentrations (PRED); B Polymyxin B concentration versus individual predicted concentrations (IPRED); C Conditional weighted residuals versus population predicted concentrations (CWRES vs. PRED); D Conditional weighted residuals versus time (CWRES vs. Time); The blue lines in panels (C, D) represent smoothed regression lines
