Table 1.

Distribution of statistically significant allele and genotype frequencies in PCa patients and HCs. Values in bold represent significant results.

Gene	SNP ID	Gene Feature	Gentoypes, Alleles	PCa N (F)	HCs N (F)	OR	95% CI	p-Value
IL4R	rs2301807	intronic	AA	22 (0.512)	0 (0.000)	Ref
			AC	1 (0.023)	0 (0.000)	0.067	0.001–4.693	Ns
			CC	20 (0.465)	32 (1.000)	0.014	0.001–0.244	<0.0001
			A	45 (0.523)	0 (0.000)	Ref
			C	41 (0.477)	64 (1.000)	0.007	0.000–0.118	<0.0001
IL12RB1	rs3746190	3′ UTR	GG	22 (0.500)	12 (0.353)	Ref
			GA	22 (0.500)	18 (0.529)	0.667	0.261–1.706	ns
			AA	0 (0.000)	4 (0.118)	0.062	0.003–1.243	0.013
			G	66 (0.750)	42 (0.618)	Ref
			A	22 (0.250)	26 (0.382)	0.538	0.271–1.070	ns
IL12RB2	rs2307145	missense	GG	38 (0.950)	24 (0.800)	Ref
			GC	2 (0.050)	5 (0.167)	2.857	0.045–1.407	ns
			CC	0 (0.000)	1 (0.033)	0.625	0.008–5.419	ns
			G	78 (0.975)	53 (0.883)	Ref
			C	2 (0.025)	7 (0.117)	0.194	0.039–0.971	0.038
IL6	rs2069832	intronic	AA	1 (0.083)	2 (0.027)	Ref
			AG	10 (0.500)	12 (0.270)	1.667	0.131–21.195	ns
			GG	26 (0.417)	10 (0.703)	5.200	0.423–63.909	ns
			A	12 (0.162)	16 (0.333)	Ref
			G	62 (0.838)	32 (0.667)	2.583	1.092–6.114	0.028
TMPRSS2	rs140141551	intronic	CC	39 (0.830)	40 (0.976)	Ref
			CA	8 (0.170)	1 (0.024)	8.205	0.980–68.710	0.024
			AA	0 (0.000)	0 (0.000)	1.025	0.020–52.950	ns
			C	86 (0.915)	81 (0.988)	Ref
			A	8 (0.150)	1 (0.012)	7.535	0.922–61.586	0.0382
TMPRSS2	rs11701576	intronic	AA	38 (0.884)	18 (0.667)	Ref
			AG	5 (0.116)	9 (0.333)	0.263	0.077–0.899	0.027
			GG	0 (0.000)	0 (0.000)	0.481	0.009–25.810	ns
			A	81 (0.942)	45 (0.833)	Ref
			G	5 (0.058)	9 (0.167)	0.309	0.097–0.977	0.037
ACE2	rs35803318	synonymous	CC	43 (0.915)	34 (1.000)	Ref
			CT	1 (0.021)	0 (0.000)	2.379	0.094–60.247	ns
			TT	3 (0.064)	0 (0.000)	5.552	0.277–131.141	ns
			C	87 (0.925)	68 (1.000)	Ref
			T	7 (0.075)	0 (0.000)	11.743	0.659–209.216	0.022

Abbreviations: ns, not significant; Ref, reference allele; N, number of individuals; F, frequency; OR, odds ratio; CI, confidence interval.