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. 2023 Apr 13;12(4):591. doi: 10.3390/pathogens12040591

Figure 3.

Figure 3

Structural impacts of the amino acid substitutions on protein stability, computed by DynaMut. K107E variant (A), A210S variant (B), N242S variant (C), P424L variant (D), and F512Y variant (E), with prediction outcome, ΔΔG, of 0.496, 0.271, 0.118, −0.121, and −0.804 (kcal/mol), respectively. ΔΔG = vibrational entropy change.