Table 3.
Protein variants analysed by PolyPhen-2, SNPs&GO, PROVEAN, SIFT, and PANTHER.
|
Protein Variant (XP_024839792.1) |
PolyPhen-2 | SNPs&GO | PROVEAN | SIFT | PANTHER |
|---|---|---|---|---|---|
| K107E | Benign | Neutral | Neutral | Tolerated | Probably Benign |
| A210S | Benign | Neutral | Neutral | Tolerated | Possibly Damaging |
| N242S | Benign | Neutral | Neutral | Tolerated | Probably Benign |
| P424L | Probably Damaging |
Disease | Deleterious | Deleterious | Probably Damaging |
| F512Y | Benign | Neutral | Neutral | Tolerated | Probably Benign |
Predictions of the impacts of amino acid substitutions as a result of nsSNPs on bovine CMAH using different computational tools.