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Surface Pre-Reacted Glass-ionomer (S-PRG) filler. (A) S-PRG filler is composed of three layers: outer SiO2 coating layer, pre-reacted glass-ionomer phase, and inner functional glass core. (B) S-PRG filler releases multiple ions: strontium (Sr2+), borate (BO33−), fluoride (F−), sodium (Na+), silicate (SiO32−), and aluminum (Al3+) ions.
