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. 2023 Apr 6;16(4):553. doi: 10.3390/ph16040553

Figure 1.

Figure 1

TEADi K-975 increases the response to KRASG12Ci adagrasib in several KRASG12C-NSCLC cell lines. IC50 detection at 144 h after treatment for the single and combination treatments with adagrasib and K-975. The geometric mean and SD were calculated from a minimum of three biological replicates for each cell line, ns: non statistical significant, * p-value < 0.05, ** p-value < 0.001, *** p-value < 0.0005.