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. 2023 Apr 7;12(8):2761. doi: 10.3390/jcm12082761

Table 1.

Baseline demographic and clinical characteristics of the patients.

Variable All Patients IPAH CHD–PAH Others p-Value
(n = 89) (n = 20) (n = 62) (n = 7)
Age—years 34.53 ± 8.97 36.25 ± 9.36 33.47 ± 8.58 36.29 ± 3.04 0.075
BMI—kg/m2 20.29 ± 3.35 22.30 ± 2.76 19.46 ± 3.30 21.37 ± 3.08 0.003
Smoking—yes/no 14 (15.7%)/75 (84.3%) 3 (15.0%)/17 (85.0%) 9 (14.5%)/53 (85.5%) 2 (28.6%)/5 (71.4) 0.623
Gender—female/male 74 (83.1%)/15 (16.9%) 16 (80.0%)/4 (20.0%) 52 (83.9%)/10 (16.1%) 6 (85.7%)/1 (14.3%) 0.909
Marital status 0.293
Married 58 (65.2%) 17 (85.0%) 35 (56.5%) 6 (85.7%)
Single 25 (28.1%) 2 (10.0%) 22 (35.5%) 1 (14.3%)
Divorce 6 (6.7%) 1 (5.0%) 5(8.0%) 0
Educational level 0.373
Primary school 7 (7.8%) 3 (15.0%) 3 (4.8%) 1 (14.3%)
Middle school 24 (27.0%) 4 (20.0%) 18 (29.0%) 2 (28.6%)
High school 24 (27.0%) 4 (20.0%) 20 (32.3%) 0
College or above 34 (38.2%) 9 (45.0%) 21 (33.9%) 4 (57.1%)
Course of disease (year) 5.73 ± 4.57 4.55 ± 3.85 5.95 ± 4.82 7.29 ± 4.82 0.112
WHO-FC 0.762
I 21 (23.6%) 3 (15.0%) 16 (25.8%) 2 (28.6%)
II 62 (69.7%) 15 (75.0%) 43 (69.4%) 4 (57.1%)
III 6 (6.7%) 2 (10.0%) 3 (4.8%) 1 (14.3%)
Right heart catheterization
PAP (mean)—mmHg 57.28 ± 21.67 49.50 ± 20.03 59.70 ± 22.19 53.83 ± 19.5 0.383
3wPAWP—mmHg 8.97 ± 3.15 8.67 ± 3.11 9.02 ± 3.24 9.17 ± 3.24 0.937
CI—L/min/m2 3.46 ± 1.09 3.25 ± 1.08 3.46 ± 1.08 3.84 ± 1.28 0.403
RAP—mmHg 5.03 ± 3.19 7.17 ± 5.02 4.51 ± 2.47 4.67 ± 1.86 0.201
Echocardiography
LVEF % 68.78 ± 5.74 69.10 ± 5.19 68.80 ± 5.90 67.71 ± 6.53 0.988
TAPSE mm 18.01 ± 3.84 19.84 ± 4.10 17.64 ± 3.51 16.03 ± 4.53 0.084
DASI total score 36.47 ± 13.58 33.09 ± 13.45 37.52 ± 13.39 36.84 ± 16.08 0.451
PeakVO2—mL/min/kg 13.70 ± 3.74 13.97 ± 2.26 13.71 ± 3.90 12.87 ± 7.74 0.890
Peak VO2 < 11 mL/min/kg 20 (22.4%) 4 (20.0%) 14 (22.5%) 2 (28.6%) 0.342
6MWD—meters 478.10 ± 100.80 516.45 ± 89.54 467.97 ± 103.16 467.97 ± 100.40 0.161