Table 1.
Variable | All Patients | IPAH | CHD–PAH | Others | p-Value |
---|---|---|---|---|---|
(n = 89) | (n = 20) | (n = 62) | (n = 7) | ||
Age—years | 34.53 ± 8.97 | 36.25 ± 9.36 | 33.47 ± 8.58 | 36.29 ± 3.04 | 0.075 |
BMI—kg/m2 | 20.29 ± 3.35 | 22.30 ± 2.76 | 19.46 ± 3.30 | 21.37 ± 3.08 | 0.003 |
Smoking—yes/no | 14 (15.7%)/75 (84.3%) | 3 (15.0%)/17 (85.0%) | 9 (14.5%)/53 (85.5%) | 2 (28.6%)/5 (71.4) | 0.623 |
Gender—female/male | 74 (83.1%)/15 (16.9%) | 16 (80.0%)/4 (20.0%) | 52 (83.9%)/10 (16.1%) | 6 (85.7%)/1 (14.3%) | 0.909 |
Marital status | 0.293 | ||||
Married | 58 (65.2%) | 17 (85.0%) | 35 (56.5%) | 6 (85.7%) | |
Single | 25 (28.1%) | 2 (10.0%) | 22 (35.5%) | 1 (14.3%) | |
Divorce | 6 (6.7%) | 1 (5.0%) | 5(8.0%) | 0 | |
Educational level | 0.373 | ||||
Primary school | 7 (7.8%) | 3 (15.0%) | 3 (4.8%) | 1 (14.3%) | |
Middle school | 24 (27.0%) | 4 (20.0%) | 18 (29.0%) | 2 (28.6%) | |
High school | 24 (27.0%) | 4 (20.0%) | 20 (32.3%) | 0 | |
College or above | 34 (38.2%) | 9 (45.0%) | 21 (33.9%) | 4 (57.1%) | |
Course of disease (year) | 5.73 ± 4.57 | 4.55 ± 3.85 | 5.95 ± 4.82 | 7.29 ± 4.82 | 0.112 |
WHO-FC | 0.762 | ||||
I | 21 (23.6%) | 3 (15.0%) | 16 (25.8%) | 2 (28.6%) | |
II | 62 (69.7%) | 15 (75.0%) | 43 (69.4%) | 4 (57.1%) | |
III | 6 (6.7%) | 2 (10.0%) | 3 (4.8%) | 1 (14.3%) | |
Right heart catheterization | |||||
PAP (mean)—mmHg | 57.28 ± 21.67 | 49.50 ± 20.03 | 59.70 ± 22.19 | 53.83 ± 19.5 | 0.383 |
3wPAWP—mmHg | 8.97 ± 3.15 | 8.67 ± 3.11 | 9.02 ± 3.24 | 9.17 ± 3.24 | 0.937 |
CI—L/min/m2 | 3.46 ± 1.09 | 3.25 ± 1.08 | 3.46 ± 1.08 | 3.84 ± 1.28 | 0.403 |
RAP—mmHg | 5.03 ± 3.19 | 7.17 ± 5.02 | 4.51 ± 2.47 | 4.67 ± 1.86 | 0.201 |
Echocardiography | |||||
LVEF % | 68.78 ± 5.74 | 69.10 ± 5.19 | 68.80 ± 5.90 | 67.71 ± 6.53 | 0.988 |
TAPSE mm | 18.01 ± 3.84 | 19.84 ± 4.10 | 17.64 ± 3.51 | 16.03 ± 4.53 | 0.084 |
DASI total score | 36.47 ± 13.58 | 33.09 ± 13.45 | 37.52 ± 13.39 | 36.84 ± 16.08 | 0.451 |
PeakVO2—mL/min/kg | 13.70 ± 3.74 | 13.97 ± 2.26 | 13.71 ± 3.90 | 12.87 ± 7.74 | 0.890 |
Peak VO2 < 11 mL/min/kg | 20 (22.4%) | 4 (20.0%) | 14 (22.5%) | 2 (28.6%) | 0.342 |
6MWD—meters | 478.10 ± 100.80 | 516.45 ± 89.54 | 467.97 ± 103.16 | 467.97 ± 100.40 | 0.161 |