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Illustration of the general functions of circular RNAs (circRNAs). Functions of circRNAs have been proposed in several diseases including cancers, brain or CNS disorders, several types of diabetes mellitus, bone-related diseases, and polycystic ovary syndrome. Consequently, certain circRNAs could be diagnostic and/or therapeutic tools for these diseases. The arrowhead means stimulation and/or augmentation, whereas the hammerhead represents inhibition.
