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Overview of molecular mechanisms of WS phytochemicals against SARS-CoV-2. WS phytochemicals inhibit viral entry by inhibiting SARS-CoV-2 S, E, and N proteins, as well as host ACE2, TMPRSS2, and GRP78. Meanwhile, WS phytochemicals also prevent viral replication by inhibiting the viral main protease, NSP15 endonuclease, and NSP10/NSP6 protein complex.
