Figure 1.

Schematic representations of various p53 forms generated by posttranslational modifications induced by stress factors encountered by cells. Activated p53 stimulates expression of a set of genes regardless of the type of stress (common target genes), whereas other genes (stress-specific genes) are preferentially activated only when p53 is modified in a particular fashion. While common target genes are well known, the stress-specific genes are not well recognized. P53 modifications induced by infections have been poorly studied. Created with BioRender.com (accessed on 14 February 2023).