Table 1.
Overview on (A) number of articles found in the search, (B) number of articles remaining after title and abstract screening and (C) number of articles remaining after full text screening.
| Anti-TB Drug | Retrieved Articles | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Data on Plasma Concentration | Data on Milk Concentration | Data on Plasma Concentration in Breastfed Infant | |||||||
| A | B | C | A | B | C | A | B | C | |
| PK studies, including population kinetics | |||||||||
| Bedaquiline | 7 | 3 | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
| Clofazimine | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 |
| Cycloserine /Terizidone |
17 | 9 | 5 | 0 indirect information, no access to the original publication |
0 indirect information, no access to the original publication |
0 indirect information, no access to the original publication |
0 | 0 | 0 |
| Levofloxacin | 31 | 12 | 6 | 2 | 1 | 1 | 6 | 0 | 0 |
| Linezolid | 53 | 7 | 3 | 6 | 3 | 3 | 11 | 3 | 3 |
| Pretomanid | 14 | 4 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| Pyrazinamide | 110 | 7 | 5 | 3 | 2 | 0 | 19 | 0 | 0 |
| Streptomycin | 332 1 | 5 | 2 | 2 (Japanese language, Russian language) | 8 | 0 | 0 | ||
| PK studies, modelling approaches | |||||||||
| Ethambutol | 2 2 | 0 | 0 | 1 | 1 | 1 | 6 | 1 3 | n.a. |
| INH | 22 2 | 2 | 0 | No new data after 2017 | 9 | 1 4 | n.a. | ||
| Rifampicin | 141 2 | 3 | 0 | 7 | 1 | 1 | 14 | 1 3 | n.a. |