Table 3. Biomarkers and their correlation with clinical data.
| Gender | p-value | Weight (g) | p-value | GA (weeks) | p-value | SGA | p-value | CNS (IG ≤30) | p-value | Acidemia (pH≤7,2) | p-value | Asphyxia (Apgar ≤3) | p-value | Survival (hours) | p-value | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKT-3 | Male 8727±5578 |
0.094* | <1000 7483±3067 |
0.089* | ≤30 8713±5119 |
0.089* | No 7956±4978 |
0.451* | No 7001±4550 |
0.032* | No 8612±6162 |
0.662* | No 7538±4864 |
0.300* | Until 24h 7202±4515 |
0.666* |
| 1000 a <1500 9778±6714 |
31 a 36 7302±4811 |
25–72h 8116±5228 |
||||||||||||||
| Female 6641±3503 |
≥1500 7033±4504 |
≥37 6609±4245 |
Yes 6967±4280 |
Yes 8713±5119 |
Yes 7446±4122 |
Yes 8526±4948 |
Over 72h 8157±4889 |
|||||||||
| NF-Kb | Male 7401±3974 |
0.342* | <1000 8536±435 |
0.054* | ≤30 8521±4112 |
0.092* | No 8000±4154 |
0.194* | No 7023±3787 |
0.045* | No 7707±4588 |
0.735* | No 7970±4126 |
0.402* | Until 24h 6374±3200 |
0.037** |
| 1000 a <1500 8329±3313 |
31 a 36 7381±3858 |
25–72h 8064±3958 |
||||||||||||||
| Female 8195±4034 |
≥1500 6920±4025 |
≥37 6572±3720 |
Yes 6103±2243 |
Yes 8521±4112 |
Yes 7775±3725 |
Yes 7775±3725 |
Over 72h 8899 ± 4529 |
|||||||||
| Parkin | Male 570±440 |
0.726* | <1000 750±420 |
<0.001* | ≤ 30 690±460 |
<0.001* | No 510±400 |
0.014* | No 420±300 |
<0.001* | No 630±430 |
0.355* | No 520±380 |
0.179* | Until 24h 550±420 |
0.988* |
| 1000 a <1500 600±450 |
31 a 36 490±350 |
25–72h 510±340 |
||||||||||||||
| Female 510±360 |
≥1500 390±310 |
≥ 37 310±190 |
Yes 730±410 |
Yes 690±460 |
Yes 510±390 |
Yes 610±460 |
Over 72h 490±490 |
|||||||||
| TRK-C | Male 870±560 |
0.179 | <1000 1090±68 |
0.073* | ≤30 1040±680 |
0.137* | No 910±600 |
0.266* | No 850±510 |
0.098* | No 1050±720 |
0.197* | No 960±600 |
0.481* | Until 24h 870±570 |
0.545* |
| 1000 a <1500 1000±660 |
31 a 36 920±520 |
25–72h 1010±63 |
||||||||||||||
| Female 1020±650 |
≥1500 800±490 |
≥37 740±470 |
Yes 1090±570 |
Yes 1040±680 |
Yes 880±530 |
Yes 870±610 |
Over 72h 900±590 |
|||||||||
| VEGFR1 | Male 629±1021 |
0.221* | <1000 881±1427 |
0.668* | ≤ 30 908±1397 |
0.528* | No 648±1014 |
0.637* | No 551±1010 |
0.286* | No 899±1625 |
0.928* | No 778±1247 |
0.025* | Until 24h 697±1343 |
0.180* |
| 1000 a <1500 894±1312 |
31 a 36 574±1252 |
25–72h 941±1418 |
||||||||||||||
| Female 823±1412 |
≥1500 526±996 |
≥37 521±576 |
Yes 1125±2026 |
Yes 908±1397 |
Yes 632±963 |
Yes 572±1137 |
Over 72h 387±293 |
GA: gestational age; SGA: small for gestational age; CNS: central nervous system. *p obtained by Student’s t-teste. Bold indicates statistically significant p-values.