Figure 3.

Association between progression-free survival and clinical variables: (A) Forest plots representing hazard ratios and confidence intervals for univariate (gray) and multivariate (purple) Cox models for progression-free survival estimated using clinical variables in the training cohort. *: Log-rank test p-value ≤ 0.1. (B,C) Kaplan–Meier curves with patients stratified according to the clinical model dichotomized by training median (High vs. Low) for progression-free survival for training cohort (B) and validation cohort (C). ICI: Immune Checkpoint Inhibitor; PD-L1: Programmed Death-Ligand 1; PD-1; Programmed cell Death protein-1; CTLA-4: Cytotoxic T Lymphocyte-Associated protein 4; WHO: World Health Organization.