Table 5.
Univariate and multivariate analyses for OS in 104 patients with high-risk PCa.
| Variable | Univariate Model | Multivariate Model | ||||
|---|---|---|---|---|---|---|
| HR | 95% CI | p | HR | 95% CI | p | |
| CTC (GILUPI) | 0.65 | 0.37–1.16 | 0.147 | |||
| CTC (EPISPOT) | 0.68 | 0.37–1.23 | 0.199 | |||
| CTC (CellSearch®) | 4.87 | 2.09–11.32 | <0.001 | 1.24 | 0.48–3.20 | 0.654 |
| CTC (any assay) | 1.15 | 0.49–2.71 | 0.752 | |||
| PSA ≥ 20 ng/mL | 0.67 | 0.35–1.28 | 0.226 | |||
| Gleason Sum ≥ 8 | 1.82 | 1.00–3.31 | 0.048 | 1.32 | 0.65–2.66 | 0.444 |
| cT ≥ 2c | 2.16 | 1.19–3.93 | 0.011 | 1.48 | 0.69–3.16 | 0.316 |
| Metastases at baseline | 14.41 | 7.08–29.30 | <0.001 | 10.20 | 4.25–24.46 | <0.001 |