Table 5.
Effect | Mediator | Phase of WH/CW |
---|---|---|
Anti-inflammatory | ROS, NO, IL | Inflammation |
Vasodilatation | NO | Proliferation |
Matrix formation | TGF-beta and MMPs | Proliferation and remodeling |
Promote epithelial cell function | Cyclin D1 | Proliferation and remodeling |
ROS: radical oxygen singlet; NO: nictric oxide; IL: interleukins; MMPs: metaloproteinases.