Table 2.
Baseline echocardiographic and dynamic SPECT parameters.
| Parameter | CMD+ n = 47 |
CMD− n = 73 |
p-Value |
|---|---|---|---|
| Echocardiographic parametrs | |||
| Left ventricle ejection fraction, % | 62 (58.5; 65.0) | 63 (61; 66) | 0.183 |
| End-systolic dimension, mm | 40 (38; 43) | 38.5 (36.5; 41.5) | 0.524 |
| End-diastolic dimension, mm | 51.0 (48.7; 53.0) | 50.5 (47.5; 52.5) | 0.307 |
| LVMMi, g/m2 | 98.0 (88.5; 114.5) | 92 (85.5; 106.5) | 0.276 |
| E/A ratio | 1.04 (0.79; 1.3) | 0.97 (0.74; 1.2) | 0.516 |
| Lateral e′, sm/s | 5.56 (4.78; 6.45) | 8.56 (8.01; 9.14) | 0.009 |
| TRV, m/s | 2.99 (2.95; 3.01) | 2.63 (2.3; 2.76) | 0.011 |
| E/e′ ratio | 14 (13.5; 15.0) | 11 (10; 12) | 0.041 |
| LAVI, mL/m2 | 38.3 (35.7; 51.1) | 29.7 (27.5; 47.9) | 0.038 |
| LV global longitudinal strain, % | −14.7 (−12.9; −16.9) | −20.9 (16.1; 21.6) | 0.005 |
| Diastolic dysfunction, n (%) | 37 (88.1) | 26 (37.1) | <0.001 |
| Dynamic SPECT parametrs | |||
| Stress-MBF, mL/min/g | 1.14 (0.67; 1.49) | 1.63 (1.19; 1.83) | <0.001 |
| Rest-MBF, mL/min/g | 0.75 (0.54; 0.99) | 0.52 (0.40; 0.69) | <0.001 |
| Myocardial flow reserve | 1.39 (1.11; 1.96) | 2.69 (2.15; 3.78) | <0.001 |
| Standard semi-quantitative indices of myocardial perfusion imaging | |||
| Summed stress score | 3 (0.5; 4) | 2.5 (0; 5) | 0.753 |
| Summed rest scores | 2 (0; 3) | 1 (0; 2) | 0.537 |
| Difference between stress and rest score | 2 (0; 3) | 2 (0; 4) | 0.975 |
Note. E/A—the ratio of the maximum blood flow rate in the phase of rapid filling to the maximum flow rate in atrial systole; E/e′—the ratio of the transmitral E peak to the tissue myocardial Doppler e′; LVMMi—left ventricular myocardial mass index; LAVI—left atrial volume indexed; TRV—tricuspid regurgitation peak velocity; lateral e′—early diastolic velocity of the lateral wall of the left ventricle.