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. 2023 Apr 8;28(8):3318. doi: 10.3390/molecules28083318

Table 1.

The amounts of compounds used for transfections in a serum-free medium (Opti-MEM) and associated cytotoxicity.

siRNA (µg) CPP-GNP (µg) CPP, Max. (µg/µM) CPP Cytotoxicity (24 h) CPP Cytotoxicity (48 h)
0.1 4 1.3/4.4 Non-cytotoxic Non-cytotoxic
0.3 12 3.8/13 Non-cytotoxic 12–24%
0.7 28 9/31 50% n/d *
1.0 40 12.8/44 90% 11–29%
0 0 28/95 n/d * 55–88%
0 0 45/153 n/d * 98%

* n/d stands for “not determined”.