A 78-year-old patient with a diagnosis of urothelial carcinoma. (A–D) PET, CT, fused PET/CT, and PET maximum intensity projection of baseline FDG-PET/CT, respectively. A discreet liver focal liver uptake corresponds to a small hypodensity in unenhanced CT. It was overlooked at the time of diagnosis and the patient underwent a cystectomy with an enterocystoplasty procedure. (E) Follow-up contrast-enhanced CT at 3 months shows an enlargement of the hepatic hypodensity, evocative of its metastatic origin. This case shows that although liver metastases are rare at the time of bladder cancer diagnosis, their detection is paramount.