Table 2.
Cardiovascular markers significantly linked to gut microbiome composition at the level of bacterial cooperatives. Samples are pooled across the groups.
| Cooperative Used as a Balance Numerator | Factor | Linear Model Coefficient | p | FDR | Number of Subjects |
|---|---|---|---|---|---|
| Lactobacillus-coop | Pulse pressure in sitting position (PP) | 0.8576 | 0 | 0.0034 | 180 |
| Lactobacillus-coop | Central systolic blood pressure (CSBP) | 0.6591 | 0.0009 | 0.0468 | 178 |
| Prevotellaceae-coop | Pulse Wave Velocity (PWV) | 0.6488 | 0.0003 | 0.0357 | 175 |
| Prevotellaceae-coop | Pulse pressure in sitting position (PP) | 0.5846 | 0.001 | 0.0468 | 180 |
| Subdoligranulum-coop | Pulse pressure in sitting position (PP) | −0.4016 | 0.0018 | 0.0703 | 180 |
| Subdoligranulum-coop | Maximum percentage of stenosis (MPS) | −0.427 | 0.0009 | 0.0468 | 180 |
| Subdoligranulum-coop | Systolic pulmonary artery pressure (sPAP) (highly correlated with: tricuspid regurgitation gradient) * | −0.4658 | 0.0002 | 0.0351 | 178 |
| Methanobrevibacter-coop | End-diastolic volume (EDV) (highly correlated with: end-diastolic size) * | −0.6481 | 0.0004 | 0.0357 | 177 |
* for each pairwise highly correlated clusters of parameters (|rho| > 0.8, see Section 2), one parameter per cluster was chosen for the analysis.