Abbreviation	Definition
DC	dendritic cells
DDS	drug delivery system
DiO	lipophilic carbocyanine fluorophore
DLS	dynamic light scattering
DOE	design of experiments
EE	encapsulation efficiency
FDA	Food and Drug Administration
FRR	flow rate ratio
GMP	good manufacturing practices
iLiNP	invasive lipid nanoparticle production device
LBNP	lipid-based nanoparticle
LN	lymph node
LNP	lipid nanoparticle
LP	lipoparticle
HFF	hydrodynamic flow focusing
mRNA	messenger RNA
NLC	nanostructured lipid carriers
PDI	polydispersity index
pDNA	plasmid DNA
PK/PD	pharmacokinetics/pharmacodynamics
PTX	Paclitaxel
SHM	staggered herringbone mixer
siRNA	small interfering RNA
SLN	solid lipid nanoparticle
SOR	sorafenib
TEM	transmission electron microscopy
TFR	total flow rate