Table 2.
Differences in signs and symptoms of COVID-19 in pregnant patients according to their body mass index.
| Variables | Body Mass Index (BMI) | p | ||
|---|---|---|---|---|
| Normal Weight n = 53 |
Overweight n = 92 |
Obese n = 47 |
||
| Clinical endpoints | ||||
| Days from COVID-19 symptom onset to hospitalization initiation, median (variance) | 3.00 (15.7) |
3.00 (20.9) |
4.00 (30.4) |
0.283 a |
| Length of hospital stay (ICU duration excluded) (days), median (variance) | 4.00 (31.5) |
5.00 (23.2) |
6.00 (66.7) |
0.045 a |
| ICU duration (days), median (variance) |
0.00 (6.3) |
0.00 (10.2) |
0.00 (66.2) |
0.039 a |
| Drug-resistant nosocomial infection, n (%) |
1 (1.9%) | 1 (1.1%) | 4 (8.5%) | 0.049 b |
| Number of patients on mechanical ventilation, n (%) | 9 (17%) | 13 (14.1%) | 13 (27.7%) | 0.143 b |
| Duration of mechanical ventilation (days), median (variance) |
0.00 (19.0) |
0.00 (26.5) |
0.00 (63.3) |
0.095 a |
| Clinical status parameters related to COVID-19 infection | ||||
| Body temperature >38 °C on admission, n (%) |
28 (52.8%) | 50 (54.3%) | 29 (61.7%) | 0.628 b |
| Cough, n (%) | 24 (45.3%) | 40 (44.0%) | 24 (51.1%) | 0.723 b |
| Difficult breathing, n (%) |
13 (24.5%) | 17 (18.5%) | 9 (19.1%) | 0.666 b |
| Headache, n (%) | 9 (17.0%) | 12 (13.0%) | 7 (14.9%) | 0.809 b |
| Smell loss, n (%) | 21 (39.6%) | 24 (26.1%) | 12 (25.5%) | 0.177 b |
| Taste loss, n (%) | 20 (37.7%) | 22 (23.9%) | 11 (23.4%) | 0.152 b |
| Diarrhea, n (%) | 0 (0.0%) | 5 (5.4%) | 1 (2.1%) | 0.175 b |
| ARDS, n (%) | 2 (3.8%) | 4 (4.3%) | 6 (12.8%) | 0.104 b |
| Pulmonary embolism, n (%) |
0 (0.0%) | 0 (0.0%) | 2 (4.5%) | 0.039 b |
| Multi-organ failure, n (%) | 1 (1.9%) | 1 (1.1%) | 4 (8.5%) | 0.049 b |
| Maternal death, n (%) | 1 (1.9%) | 1 (1.1%) | 5 (10.6%) | 0.013 b |
| Peak of deterioration (days), median (variance) | 4.00 (17.4) |
4.00 (17.5) |
6.00 (30.8) |
0.065 a |
| Diagnostic imaging | ||||
| CT, n (%) | 12 (22.6%) | 20 (21.7%) | 18 (38.3%) | 0.088 b |
| CT score, median (variance) |
8.00 (53.8) |
10.50 (27.8) |
11.00 (57.2) |
0.852 a |
| Therapy | ||||
| Average number of antibiotics prescribed per patient, median (variance) | 1.00 (1.6) |
1.0 (1.5) |
2.0 (3.3) |
0.028 a |
| Number of patients with corticosteroid therapy, n (%) |
9 (17.0%) | 6 (6.5%) | 10 (21.3%) | 0.030 b |
| LMWH, n (%) | 35 (66.0%) | 59 (64.1%) | 39 (83.0%) | 0.062 b |
a Kruskal–Wallis test; b chi square test; ICU—intensive care unit; ARDS—acute respiratory distress syndrome; MOF—multi-organ failure; CT—computerized tomography; LMWH—low-molecular-weight heparin; MV—mean value; SD—standard deviation; CI—confidence interval.