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. 2022 Aug 3;192(1):84–92. doi: 10.1093/aje/kwac144

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Heat maps of the asymptotic relative efficiencies (AREs) for natural indirect effect (NIE) and mediation proportion (MP) estimators under different levels of the outcome prevalence () and the exposure-mediator association ( or ). The ARE value in each pixel is the average of the AREs among all scenarios considered with the outcome prevalence and exposure-mediator association given. A) ARE for the NIE estimator (ARE(NIE)) in case ; B) ARE for the MP estimator (ARE(MP)) in case ; C) ARE for the NIE estimator (ARE(NIE)) in case ; D) ARE for the MP estimator (ARE(MP)) in case . OR, odds ratio.

Inline graphic — Heat maps of the asymptotic relative efficiencies (AREs) for natural indirect effect (NIE) and mediation proportion (MP) estimators under different levels of the outcome prevalence () and the exposure-mediator association ( or ). The ARE value in each pixel is the average of the AREs among all scenarios considered with the outcome prevalence and exposure-mediator association given. A) ARE for the NIE estimator (ARE(NIE)) in case ; B) ARE for the MP estimator (ARE(MP)) in case ; C) ARE for the NIE estimator (ARE(NIE)) in case ; D) ARE for the MP estimator (ARE(MP)) in case . OR, odds ratio.