Table 2.

Distribution of phenotypes according to sex in oALS and younger ALS patients.

	Male Patients					Female Patients
	Age at Diagnosis ≤80 years		Age at Diagnosis >80 years		p Value	Age at Diagnosis ≤80 years		Age at Diagnosis >80 years		p Value
	N	%	N	%		N	%	N	%
Phenotype
Bulbar	189	28.51	29	39.73	0.344	180	36.96	57	62.64	<0.001
Classic	319	48.11	28	38.36	0.010	196	40.24	24	26.37	0.008
Flail arm	35	5.28	4	5.48	0.819	23	4.72	1	1.10	0.098
Flail leg	64	9.65	11	15.07	0.373	41	8.42	4	4.40	0.156
UMNp	37	5.58	0	0.00	0.025	37	7.60	5	5.49	0.410
Respiratory	19	2.87	1	1.37	0.355	10	2.05	0	0.00	0.157
Total	663	100.00	73	100.00		487	100.00	91	100.00

UMNp: upper motor neuron predominant.