Table 2.
Prognostic factors associated with mortality of COVID-19 cohort.
| Item | HR (95%CI) | p value |
|---|---|---|
| Age | ||
| 18–49 | 1.0 | – |
| 50–62 | 1.6 (1.4, 1.9) | < 0.001 |
| 63–75 | 2.3 (2.0, 2.7) | < 0.001 |
| 76–104 | 4.3 (3.8, 4.9) | < 0.001 |
| Male gender | 1.1 (1.0, 1.2) | 0.012 |
| WBC < 3500 | 1.2 (1.0, 1.4) | 0.033 |
| WBC > 9500 | 1.8 (1.7, 2.0) | < 0.001 |
| Neutrophils count > 6300 | 0.6 (0.5, 0.6) | < 0.001 |
| Lymphocyte count < 1200 | 1.1 (1.0, 1.2) | 0.009 |
| MCV < 80 | 0.8 (0.8, 0.9) | 0.001 |
| CRP > 10 | 1.4 (1.2, 1.6) | < 0.001 |
| PCO2 > 50 | 1.0 (0.9, 1.1) | 0.775 |
| Cr > 1.2 | 2.1 (2.0, 2.3) | < 0.001 |
| BUN > 23 | 2.9 (2.6, 3.3) | < 0.001 |
| Potassium > 5.1 | 2.1 (1.9, 2.4) | < 0.001 |
| PT > 12.5 | 1.1 (1.0, 1.1) | < 0.001 |
| Log ALP* | 1.4 (1.3, 1.5) | < 0.001 |
| Total bilirubin > 1.2 | 1.6 (1.4, 1.7) | < 0.001 |
| Direct bilirubin > 0.3 | 1.7 (1.5, 1.9) | < 0.001 |
| CPK > 200 | 1.4 (1.3, 1.6) | < 0.001 |
| Log CK-MB* | 1.4 (1.3, 1.4) | < 0.001 |
| LDH > 250 | 1.2 (0.8, 1.9) | 0.404 |
| Troponin > 0.04 | 2.5 (2.3, 2.8) | < 0.001 |
| D-DIMER > 250 | 1.4 (1.2, 1.7) | < 0.001 |
Footnote The Cox regression was used to analyze the impact of the variable on time to death of patients with COVID-19. MCV Mean corpuscular volume, CRP C-reactive protein, Cr Creatinine, BUN Blood urea nitrogen, PT Prothrombin time, ALP Alkaline phosphatase, CPK Creatine kinase, LDH Lactate dehydrogenase.
*The CK-MB and ALP are presented in logarithmic scale since the non-logarithmic hazard ratio is close to 1, and logarithmic transformation was used to facilitate interpretation.