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. 2023 Mar 26;11(4):735. doi: 10.3390/vaccines11040735

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© 2023 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Omicron spike-RBD-specific memory B cells detected by the MiSelect R II system after boost vaccination. (A) Blood was collected 4 weeks after a 3rd vaccine shot (T4). (B) CD19+, CD27+, IgG+, wildtype or Omicron spike-RBD+, CD3- specific MBCs in PBMC samples from mRNA boost vaccination (n = 6). (C) Concentration of neutralizing anti-wildtype-RBD or anti-Omicron-RBD IgG antibodies in plasma sample from mRNA boost vaccination (n = 6).