Table 1.
General characteristics and the selected biochemical blood parameters and tryptophan intake in the control group (n = 40) and in patients with diarrhea-predominant irritable bowel syndrome (IBS-D, n = 80); average ± SD.
| Feature | Group I (Control) |
Group II (IBS-D) |
|---|---|---|
| Age (years) | 46.5 ± 10.6 | 44.3 ± 11.4 |
| Gender M/F | 8/32 | 9/31 |
| BMI (kg/m2) | 23.5 ± 2.3 | 22.9 ± 1.9 |
| GFR (mL/min) | 94.8 ± 5.8 | 96.1 ± 4.7 |
| ALT (µ/L) | 16.8 ± 3.4 | 17.2 ± 4.4 |
| AST (µ/L) | 14.2 ± 2.5 | 15.1 ± 2.5 |
| CRP (mg/L) | 4.2 ± 1.9 | 5.1 ± 1.7 |
| FC (µg/g) | 31.6 ± 18.8 | 2.9 ± 16.9 |
| TRP (mg/24/h) | 1281 ± 146 | 1306 ± 129 |
| TRP (mg/kg b.w.) | 20.8 ± 2.46 | 21.3 ± 2.16 |
GFR—glomerular filtration rate, ALT—alanine aminotransferase, AST—aspartate aminotransferase, CRP—C-reactive protein, FC—fecal calprotectin; TRP—tryptophan intake; data are presented as average ± SD; differences between groups were not significant.