Skip to main content
. 2023 Apr 15;15(4):284. doi: 10.3390/toxins15040284

Table 1.

Longitudinal changes in clinical variables and pain scales from baseline to Cy-4.

Mean (SD) Baseline Cy-4 p
Female n, (%) 122 (80.3)
Age 51.5 (11.3)
Monthly Headache Days 20.4 (6.9) 13.4 (7.8) <0.001
Monthly Acute Medication Intake 20.9 (14.3) 14.3 (14.4) <0.001
MIDAS 74.1 (64.7) 42.6 (44.9) <0.001
HIT-6 66.7 (5.7) 64.0 (6.2) <0.001
NRS 8.9 (1.4) 8.07 (1.6) <0.001
PPI 4.0 (0.8) 3.7 (0.9) <0.001
BRS-6 4.4 (0.7) 3.9 (0.9) <0.001
mean (SD) baseline Cy-4 p
McGill Pain Questionnaire
Sensory dimension of pain experience
Throbbing 1.7 (1.3) 1.4 (1.2) 0.004
Shooting 0.8 (1.2) 0.8 (1.2) 0.956
Stabbing 0.9 (1.2) 0.8 (1.2) 0.444
Sharp 0.3 (0.8) 0.4 (0.9) 0.313
Cramping 1.0 (1.3) 1.1 (1.2) 0.797
Gnawing 1.5 (1.4) 1.3 (1.9) 0.389
Hot-burning 0.3 (0.8) 0.3 (0.7) 1.000
Aching 0.9 (1.3) 0.8 (1.2) 0.242
Heavy 0.9 (1.3) 0.8 (1.2) 0.281
Tender 0.7 (1.1) 0.6 (1.0) 0.484
Splitting 1.3 (1.4) 1.0 (1.3) 0.018
Affective dimension of pain experience
Tiring—exhausting 1.3 (1.4) 1.2 (1.3) 0.254
Sickening 1.4 (1.3) 1.1 (1.2) 0.017
Fearful 0.4 (0.9) 0.4 (0.9) 0.748
Punishing—cruel 1.4 (1.4) 1.3 (1.3) 0.218

Highlighted in bold are values for which p < 0.05.