Table 2.
Comparison of antimicrobial susceptibility among multi-resistant P. aeruginosa isolates.
| Antibiotics | Total n (%) (Total = 3579) |
P. aeruginosa Isolates | p-Value | |||
|---|---|---|---|---|---|---|
|
P. aeruginosa n (%) (Total = 2798) |
MDR n (%) (Total = 348) |
XDR n (%) (Total = 422) |
PDR n (%) (Total = 11) |
|||
| Ceftazidime | ||||||
| Sensitive | 2529 (70.7) | 2498 (89.3) | 25 (7.2) | 6 (1.4) | 0 (0) | <0.001 ** |
| Intermediate | 117 (3.3) | 78 (2.8) | 31 (8.9) | 8 (1.9) | 0 (0) | |
| Resistant | 933 (26.1) | 222 (7.9) | 292 (83.9) | 408 (96.7) | 11 (100) | |
| Cefepime | ||||||
| Sensitive | 2617 (73.1) | 2567 (91.7) | 42 (12.1) | 8 (1.9) | 0 (0) | <0.001 ** |
| Intermediate | 92 (2.6) | 33 (1.2) | 39 (11.2) | 20 (4.7) | 0 (0) | |
| Resistant | 870 (24.3) | 198 (7.1) | 267 (76.7) | 394 (93.4) | 11 (100) | |
| Ciprofloxacin | ||||||
| Sensitive | 2783 (77.8) | 2554 (91.3) | 218 (62.6) | 11 (2.6) | 0 (0) | <0.001 ** |
| Intermediate | 159 (4.4) | 95 (3.4) | 36 (10.3) | 28 (6.6) | 0 (0) | |
| Resistant | 637 (17.8) | 149 (5.3) | 94 (27) | 383 (90.8) | 11 (100) | |
| Piperacillin-Tazobactam | ||||||
| Sensitive | 2573 (71.9) | 2516 (89.9) | 44 (12.6) | 13 (3.1) | 0 (0) | <0.001 ** |
| Intermediate | 394 (11) | 178 (6.4) | 114 (32.8) | 102 (24.2) | 0 (0) | |
| Resistant | 612 (17.1) | 104 (3.7) | 190 (54.6) | 307 (72.7) | 11 (100) | |
| Gentamicin | ||||||
| Sensitive | 3085 (86.2) | 2709 (96.8) | 274 (78.7) | 102 (24.2) | 0 (0) | <0.001 ** |
| Intermediate | 77 (2.2) | 38 (1.4) | 12 (3.4) | 27 (6.4) | 0 (0) | |
| Resistant | 417 (11.7) | 51 (1.8) | 62 (17.8) | 293 (69.4) | 11 (100) | |
| Amikacin | ||||||
| Sensitive | 3313 (92.6) | 2776 (99.2) | 317 (91.1) | 220 (52.1) | 0 (0) | <0.001 ** |
| Intermediate | 66 (1.8) | 7 (0.3) | 9 (2.6) | 50 (11.8) | 0 (0) | |
| Resistant | 200 (5.6) | 15 (0.5) | 22 (6.3) | 152 (36) | 11 (100) | |
| Imipenem | ||||||
| Sensitive | 2365 (66.1) | 2270 (81.1) | 85 (24.4) | 10 (2.4) | 0 (0) | <0.001 ** |
| Intermediate | 158 (4.4) | 139 (5) | 16 (4.6) | 3 (0.7) | 0 (0) | |
| Resistant | 1056 (29.5) | 389 (13.9) | 247 (71) | 409 (96.9) | 11 (100) | |
| Meropenem | ||||||
| Sensitive | 2555 (71.4) | 2446 (87.4) | 99 (28.4) | 10 (2.4) | 0 (0) | <0.001 ** |
| Intermediate | 108 (3) | 88 (3.1) | 15 (4.3) | 5 (1.2) | 0 (0) | |
| Resistant | 916 (25.6) | 264 (9.4) | 234 (67.2) | 407 (96.4) | 11 (100) | |
| Colistin | ||||||
| Sensitive | 3234 (90.4) | 2546 (91) | 308 (88.5) | 380 (90) | 0 (0) | <0.001 ** |
| Intermediate | 305 (8.5) | 241 (8.6) | 33 (9.5) | 31 (7.3) | 0 (0) | |
| Resistant | 40 (1.1) | 11 (0.4) | 7 (2) | 11 (2.6) | 11 (100) | |
| Levofloxacin | ||||||
| Sensitive | 2587 (72.3) | 2412 (86.2) | 155 (44.5) | 20 (4.7) | 0 (0) | <0.001 ** |
| Intermediate | 261 (7.3) | 179 (6.2) | 65 (18.7) | 17 (4) | 0 (0) | |
| Resistant | 729 (20.4) | 207 (6.4) | 126 (36.2) | 385 (91.2) | 11 (100) | |
| Aztreonam | ||||||
| Sensitive | 2124 (59.3) | 2043 (73) | 54 (15.5) | 27 (6.4) | 0 (0) | <0.001 ** |
| Intermediate | 381 (10.6) | 306 (10.9) | 40 (11.5) | 35 (8.3) | 0 (0) | |
| Resistant | 1065 (29.8) | 442 (15.8) | 253 (72.7) | 359 (85.1) | 11 (100) | |
* Statistically significant; the number of * represents the degree of significance.