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(A) Apoptosis (Annexin V/PI) of KAN0441571C in 5 lung cancer cell lines (EC50 values are shown to the upper left). (B) Western blots of apoptotic proteins BCL-2, MCL-1, BAX, PARP, and caspases-3, 8, and 9 after 24 h of incubation with KAN0441571C in NCI-H23 cells. One representative data of three individual experiments are shown. (C) Densitometric measurements of protein bands in Figure 3B expressed as total protein/actin intensity.
