Table 2.
Global population coverage of the PP19128R vaccine for HLA I and II alleles.
| Population/Area | Class I | Class II | ||||
|---|---|---|---|---|---|---|
| Coverage a | Average_hit b | Pc90 c | Coverage a | Average_hit b | Pc90 c | |
| Central Africa | 57.38% | 1.32 | 0.23 | 82.75% | 2.79 | 0.58 |
| East Africa | 61.10% | 1.2 | 0.26 | 89.22% | 3.63 | 0.93 |
| East Asia | 85.63% | 2.29 | 0.7 | 73.85% | 2.72 | 0.38 |
| Europe | 82.00% | 1.76 | 0.56 | 99.06% | 4.41 | 1.4 |
| North Africa | 65.52% | 1.42 | 0.29 | 80.01% | 4.04 | 0.5 |
| North America | 82.17% | 1.88 | 0.56 | 99.93% | 5.05 | 2.94 |
| Northeast Asia | 92.53% | 2.66 | 1.12 | 97.97% | 5.07 | 2.19 |
| Oceania | 76.33% | 1.38 | 0.42 | 97.55% | 4.78 | 2.05 |
| South America | 65.56% | 1.29 | 0.29 | 98.12% | 4.69 | 2.37 |
| South Asia | 70.59% | 1.83 | 0.34 | 97.75% | 5.68 | 1.65 |
| Southeast Asia | 91.15% | 2.63 | 1.05 | 88.86% | 3.84 | 0.9 |
| Southwest Asia | 64.29% | 1.34 | 0.28 | 83.80% | 4.01 | 0.62 |
| West Africa | 59.42% | 1.33 | 0.25 | 88.35% | 4.03 | 0.86 |
| World | 82.24% | 1.88 | 0.56 | 93.71% | 4.16 | 1.25 |
a Projected population coverage. b Average number of epitope hits/HLA combinations recognized by the population. c Minimum number of epitope hits/HLA combinations recognized by 90% of the population.