Figure 3.

Cytokine levels in preterm infants, term infants, and adults following bacterial and viral TLR stimulation. Following 24 h stimulation with LPS, LTA, poly I:C, R848 and CpG-ODN 2216, supernatant cytokine concentrations from preterm infants (P, n = 10), term infants (T, n = 10), and adults (A, n = 5) samples were measured using a commercial multiplex bead array kit and an ELISA (for IFNα). Fold-change values are presented as the median ± IQR. Analyses were performed using a Kruskal-Wallis test with a Dunn’s post-hoc test. * p < 0.05.