Table 2.

Summary of approved and under-trial cisplatin analogs.

Platinum Complex	Possible Applications	Current Approval Status	References
Cisplatin	Ovarian cancer Testicular cancer Head and neck cancer Bladder cancer	Approved and used in cancer therapy since 1978	[6,85]
Carboplatin	Ovarian cancer Non-small-cell lung cancer Breast cancer Cervical cancer Testicular cancer	Approved and used in cancer therapy since 1989	[85,137,138]
Oxaliplatin	Colon cancer Gastric cancer Esophageal cancer Ovarian cancer Testicular cancer	Approved and used in cancer therapy since 1999 in Europe and 2002 in the USA	[85,91]
Nedaplatin	Non-small-cell lung cancer Esophageal cancer Head and neck cancer Ovarian cancer Urothelial cancer	In clinical trials. Approved and used in cancer therapy since 1995 in Japan	[85,139]
Heptaplatin	Gastric cancer Head and neck cancer	In clinical trials. Approved and used in cancer therapy since 2005 in Korea	[6,85]
Lobaplatin	Breast cancer Small-cell lung cancer Ovarian cancer Cervical cancer Gastric cancer	In clinical trials. Approved and used in cancer therapy since 2004 in China	[85,140,141]