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. 2023 Apr 3;15(4):1127. doi: 10.3390/pharmaceutics15041127

Table 1.

The comparison between LNPs and liposomes.

Differences Similarities
LNP
  • (1)

    Self-assembly

  • (2)

    Phospholipid monolayer structure

  • (3)

    The microfluidic preparation method

Shape, particle size distribution, positive charge, lipid composition
Liposome
  • (1)

    High energy dispersion

  • (2)

    Phospholipid bilayer structure

  • (3)

    Thin-film dispersion method