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. 2023 Apr 14;14:1130217. doi: 10.3389/fimmu.2023.1130217

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Copyright © 2023 Yang, Ren and Wang

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Association between HPV immunization and RA in US adults. (A) Among all participants, the prevalence of RA in adults was significantly decreased in the HPV-vaccinated group compared with the HPV-unvaccinated control group. (B) In the three MLR models, the adjusted OR value of HPV immunization and RA in American adults aged 18-59 was significantly decreased, but it was only statistically significant in weighted models. Model A was only adjusted for age and gender. Model B was adjusted for the confounding covariates with the numerical missing ratio below 5%. Model C was further adjusted for all confounding covariates. HPV, Human papillomavirus; BMI, body mass index; DM, diabetes mellitus; MLR, multivariate logistic regression.