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. 2023 Apr 14;14:1130217. doi: 10.3389/fimmu.2023.1130217

Table 4.

Demographic characteristics of HPV immunization cohort before and after weighting, grouped by RA.

Before weighting After weighting
RA Non-RA P value RA Non-RA P value
N = 281 N = 8663 N = 2268282 N = 66720714
Age (years, mean ± SD) 47.09 ± 8.5 39 ± 11.16 <0.001 47.2 ± 8.57 39.37 ± 11.13 <0.001
Gender, n (%)
 Male 70 (24.9) 3319 (38.3) <0.001 490556 (21.6) 25515797 (38.2) <0.001
 Female 311 (75.1) 5344 (61.7) <0.001 1777727 (78.4) 41204918 (61.8) <0.001
Race/ethnicity, n (%)
 Mexican American 35 (12.5) 1410 (16.3) 0.087 297604 (13.1) 11874722 (17.8) <0.001
 Other Hispanic 41 (14.6) 867 (10) 0.012 357612 (15.8) 6347135 (9.5) <0.001
 Non-Hispanic White 126 (44.8) 3261 (37.6) 0.014 1042612 (46) 24761259 (37.1) <0.001
 Non-Hispanic Black 58 (20.6) 1521 (17.6) 0.182 413977 (18.3) 12436207 (18.6) <0.001
 Other race 21 (7.5) 1604 (18.5) <0.001 156477 (6.9) 11301391 (16.9) <0.001
Education, n (%)
 Under high school 79 (28.1) 1726 (19.9) 0.001 666355 (29.4) 13742359 (20.6) <0.001
 High school or equivalent 65 (23.1) 1658 (19.1) 0.095 564309 (24.9) 12890995 (19.3) <0.001
 Above high school 137 (48.8) 5279 (60.9) <0.001 1037619 (45.7) 40087361 (60.1) <0.001
Marital status, n (%)
 Married/cohabiting 172 (61.2) 5650 (65.2) 0.165 1433247 (63.2) 43416038 (65.1) <0.001
 Widowed/divorced/separated 76 (27) 1007 (11.6) <0.001 583219 (25.7) 8265534 (12.4) <0.001
 Never married 33 (11.7) 2006 (23.2) <0.001 251816 (11.1) 15039142 (22.5) <0.001
 BMI (mean ± SD) 32.59 ± 8.68 28.89 ± 7.35 <0.001 33.01 ± 7.1 29.64 ± 6.58 <0.001
Smoking status, n (%)
 Every day 145 (51.6) 3929 (45.4) 0.038 1100094 (48.5) 30063106 (45.1) <0.001
 Some days 22 (7.8) 979 (11.3) 0.069 203900 (9) 7375291 (11.1) <0.001
 Not at all 114 (40.6) 3757 (43.3) 0.363 964289 (42.5) 29256853 (43.8) <0.001
Diabetes, n (%)
 Yes 7 (2.5) 368 (4.2) 0.148 57481 (2.5) 3001784 (4.5) <0.001
 No 273 (97.2) 8190 (94.5) <0.001 2193089 (96.7) 62882297 (94.2) <0.001
 Borderline 1 (0.4) 103 (1.2) 0.2 17713 (0.8) 828452 (1.2) <0.001
Hypertension, n (%) 128 (45.6) 1790 (20.7) <0.001 1062189 (46.8) 14879638 (22.3) <0.001
Hyperlipidemia, n (%) 123 (43.8) 2080 (24) <0.001 998235 (44) 16617759 (24.9) <0.001

The bold values means statistical significance.

HPV, Human papillomavirus; BMI, body mass index; DM, diabetes mellitus.