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. 2023 Apr 19;12(8):2971. doi: 10.3390/jcm12082971

Figure 3.

Figure 3

Changes in health-related quality of life based on minimal important difference. Legend: HRQOL (health-related quality of life); GHS (global health status). (A,B): Minimal important difference for improvement: global health status = 5 points; physical function = 6 points; social function = 6 points; role function = 9 points; fatigue = 6 points; pain = 9 points; appetite loss = 8 points; constipation = 13 points/Minimal important difference for deterioration: global health status = −5 points; physical function = −7 points; social function = −5 points; role function = −9 points; fatigue = −9 points; pain = −12 points; appetite loss = 8 points; constipation = −10 points [70].