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. 2023 Apr 12;15(4):950. doi: 10.3390/v15040950

Figure 1.

Figure 1

Schematic representation of HIV NL4.3 and the MUT1 and MUT 2 mutations acquired to become resistant to dCA in vitro. (A) Mutations found across the genome. (B) Details of the mutations present in the HIV-1 5′ LTR. In green, mutations found in MUT1 dCA-resistant HIV-1 variant; in blue, mutations found in MUT2 dCA-resistant HIV-1 variant and in red, mutations found in both MUT1 and MUT2 dCA-resistant HIV-1 variants. The green rectangle depicts a 49-nucleotide insertion found in a MUT1 variant. Amino acid changes are indicated in parenthesis. Previously published in Mousseau et al., mBio 2019 [5].