Skip to main content

View full-text article in PMC

. 2023 Apr 17;12(4):606. doi: 10.3390/pathogens12040606

Table 1.

In vitro susceptibility of 80 terbinafine-susceptible and resistant Trichophyton isolates to Miltefosine and five routine antifungal agents.

Antifungal Drug	Group	MIC (μg/ML)
Antifungal Drug	Group	Range	MIC₅₀	MIC₉₀	GM	Mode
Itraconazole	Terbinafine-resistant	0.016–16	0.125	1	0.140	0.063
	Terbinafine-susceptible	0.016–0.25	0.063	0.125	0.048	0.032
	Total	0.016–16	0.063	0.25	0.082	0.063
Terbinafine	Terbinafine-resistant	4–>4	4	4	4.000	4
	Terbinafine-susceptible	0.004–2	0.032	0.25	0.045	0.032
	Total	0.004–<4	2	4	0.423	4
Butenafine	Terbinafine-resistant	4–<4	4	4	4.000	4
	Terbinafine-susceptible	0.004–2	0.125	0.25	0.086	0.125
	Total	0.004–<4	2	4	0.586	4
Tolnaftate	Terbinafine-resistant	0.016–<16	16	16	7.340	16
	Terbinafine-susceptible	0.032–0.5	0.125	0.5	0.139	0.25
	Total	0.016–<16	0.5	16	1.011	16
Ketoconazole	Terbinafine-resistant	0.032–1	0.25	0.5	0.264	0.25
	Terbinafine-susceptible	0.125–0.25	0.125	0.25	0.157	0.125
	Total	0.032–1	0.25	0.5	0.203	0.125
Miltefosine	Terbinafine-resistant	0.063–0.5	0.125	0.25	0.154	0.125
	Terbinafine-susceptible	0.125–0.25	0.25	0.25	0.183	0.25
	Total	0.063–0.5	0.125	0.25	0.168	0.125