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. 2023 Apr 17;15(4):1256. doi: 10.3390/pharmaceutics15041256

Table 1.

The quality assessment checklist of the 17 included clinical trials using the Joanna Briggs Institute critical appraisal tool for randomized controlled trials.

First Author, Year Q1 Q2 Q3 Q4 Q5 Q6 Q7 Q8 Q9 Q10 Q11 Q12 Q13 Quality Index
Isolauri 2000 [41] unclear unclear YES YES YES YES YES YES unclear YES YES YES YES Medium-high
Kirjavainen 2003 [42] unclear unclear YES YES NO YES YES YES unclear YES YES YES YES Medium-high
Viljanen 2005 [43] YES YES YES YES YES YES YES YES unclear YES YES YES YES Excellent
Weston et al., 2005 [44] YES YES YES YES YES YES YES YES unclear YES YES YES YES Excellent
Brouwer 2006 [45] unclear unclear YES YES YES YES YES YES unclear YES YES YES YES Medium-high
Fölster-Holst 2006 [46] unclear unclear YES YES YES YES YES YES YES YES YES YES YES High
Grüber 2007 [47] YES YES YES YES YES YES YES YES YES YES YES YES YES Excellent
Woo 2010 [48] unclear unclear YES YES YES YES YES YES unclear YES YES YES YES Medium-high
Klewicka 2011 [49] unclear YES YES YES YES YES YES YES unclear YES YES YES YES High
Gore 2012 [50] YES YES YES YES YES YES YES YES YES YES YES YES YES Excellent
Han 2012 [51] YES YES YES YES YES YES YES YES YES YES YES YES YES Excellent
Wang 2015 [52] YES YES YES YES YES YES YES YES YES YES YES YES YES Excellent
Prakoeswa 2017 [53] unclear unclear YES YES YES YES YES YES unclear YES YES YES YES Medium-high
Wu 2017 [54] unclear unclear YES YES YES YES YES YES YES YES YES YES YES High
Ahn 2020 [55] unclear YES YES YES YES YES YES YES unclear YES YES YES YES High
Rather 2021 [56] YES YES YES YES YES YES YES YES unclear YES YES YES YES Excellent
Carucci 2022 [57] YES YES YES YES YES YES YES YES YES YES YES YES YES Excellent