Figure 3.

The approximate anatomical locations where T cells can access the central nervous system (CNS) in order to combat tick-borne flavivirus (TBFV) infection. Additionally, this figure describes the antigen presenting cells (APCs) located at each site, such as conventional dendritic cells (type 1 or 2, cDC1 or cDC2), or macrophages (Mφ). Among these are the choroid plexus, which is the site of cerebrospinal fluid (CSF) production, the subarachnoid vessels, and parenchymal post-capillary venules. Created with BioRender.com, accessed on 31 January 2023.